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Example 1: A penicillin solution containing 300 units/ml has a half-life of 8 days in plasma. What will the concentration be in 7 days? Solution Read this chapter of Applied Clinical Pharmacokinetics, 2e online now, exclusively on Sections; Download Chapter PDF; Share Answers to Problems. 3-9 Problems 3-11 Answers: Oxpranolol 3-18 Answers: Minoxidil 3-21 Answers: Propranolol 3-23 CHAPTER 4 I.V. Bolus Dosing I.V. Bolus dosing of Parent Basic & applied pharmacokinetic self assessment / John E. Murphy. SECTION I: SELF ASSESSMENT AND ANSWERS Self Assessment Problems . Useful Pharmacokinetic Equations. Symbols. D = dose τ = dosing interval. CL = clearance. Vd = volume of distribution ke = elimination rate constant. Solutions are provided for three of the problem sets. Drug Metabolism 2 (PDF), Solutions are not available. Lecture 7. Fundamentals (PDF) · Solutions to